RPS-BLAST 2.2.9 [May-01-2004]
Query= local sequence: lcl|tmpseq_0 unnamed protein product
(338 letters)
Database: cdd.v2.00
| PSSMs producing significant alignments: |
Score
(bits) |
E
value |
| |
| gnl|CDD|15384 |
pfam01628, HrcA, HrcA protein C terminal domain. HrcA is found... |
64.5 |
2e-11 |
| gnl|CDD|11135 |
COG1420, HrcA, Transcriptional regulator of heat shock gene [T... |
249 |
5e-67 |
| gnl|CDD|12118 |
COG2524, COG2524, Predicted transcriptional regulator, contain... |
36.8 |
0.003 |
gnl|CDD|15384, pfam01628, HrcA, HrcA protein C terminal domain. HrcA is found to negatively regulate the transcription of heat shock genes. HrcA contains an amino terminal helix-turn-helix domain, however this corresponds to the carboxy terminal domain.
CD-Length = 222 residues, 93.2% aligned
Score = 64.5 bits (157), Expect = 2e-11
Query: 117 EKVLFLAGNLLARLTEGYVLIERPNTRDLKILRVMLIPVSEDYLIFSILTEFGVSKVTPI 176
Sbjct: 2 DKLLQRAAEILSELTGYTAVVLGPELSKDRLKHIELIPLDPHRALAVLVTDSGHVENRTI 61
Query: 177 KTQERLNWEEIERQLNFL---LRGRTVGEVLMGKIESLKGS----------GFLRLIESL 223
Sbjct: 62 TLPANISESDLEKASNILNDRLRGLTLSEIH-QKLETELPQLLSEYFKVYDEVLDLFESI 120
Query: 224 IGETVERYLD-AGLENLLKDETLT-LEDIRNLL-----EEVKDQKFLESLVGEGITVRIG 276
Sbjct: 121 FEEDEFEKLYVGGKSNLLNQPEFADLEKLRQLLSLLEQERVLIRLLLADIDMSGVTVRIG 180
Query: 277 REIGRKKLEKFAVFSGKYFKGESPIGSV 304
Sbjct: 181 KENKLESLSDCSVISSPYKIGERPLGAL 208
gnl|CDD|11135, COG1420, HrcA, Transcriptional regulator of heat shock gene [Transcription]
CD-Length = 346 residues, 100.0% aligned
Score = 249 bits (636), Expect = 5e-67
Query: 12 LKKLNDRQRKVLYCIVREYIENKKPVSSQRVLEVSNIEFSSATIRNDMKKLEYLGYIYQP 71
Sbjct: 1 MGKLDERQRLILRAIVEDYLATGEPVGSKTLSEKYNLDLSSATIRNEMADLEKLGLIEKP 60
Query: 72 HTSAGRIPTDKGLRFYYEEMLKISKETSEADLAVETFKSMPLADPEKVLFLAGNLLARLT 131
Sbjct: 61 HTSSGRVPTDKGYRYYVDHLLEVEDLSEEERRRIESFLESEGYDLEDLLQKAAQLLSELT 120
Query: 132 EGYVLIERPNTRDLKILRVMLIPVSEDYLIFSILTEFGVSKVTPIKTQERL---NWEEIE 188
Sbjct: 121 GLTGVVLTPKFSDESLKHIELVPLDPHRALAVLVTDSGEVENRIIELPEGITLSDLEELS 180
Query: 189 RQLNFLLRGRTVGEVLMGKIESLKGS-----GFLRLIESLIGETVE-----RYLDAGLEN 238
Sbjct: 181 NILNARLRGTTLNEIRTKLEKELPEFRRILGELVDNLLELGLHFFSLDGDSRLLVGGKAN 240
Query: 239 LLKD-ETLTLEDIRNLLEEVKDQKFLESLV-----GEGITVRIGREIGRKKLEKFAVFSG 292
Sbjct: 241 LLNQPEFSDIERLRQLLELLEDQKVLLQLLDNEEEAEGVTVFIGRENGLESLEGCSVITA 300
Query: 293 KYFKGESPIGSVYLFTSKVTKYDRNHRVFEYILNRLSEYFTSTSRR 338
Sbjct: 301 PYRIGGSPLGALGVIGPTRMDYQRVIPLVDYVAKVLSELLTKLYRY 346
gnl|CDD|12118, COG2524, COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains [Transcription]
CD-Length = 294 residues, only 30.3% aligned
Score = 36.8 bits (85), Expect = 0.003
Query: 12 LKKLNDRQRKVLYCIVREYIENKKPVSSQRVLEVSNIEFSSATIRNDMKKLEYLGYIY-Q 70
Sbjct: 1 MKELTSSQKEILQALINLYRRKKRPIKGEEIAEVLNRN--PGTVRNQMQSLKALGLVEGV 58
Query: 71 PHTSAGRIPTDKGLRFYYEEMLKISKETSEADLAVE 106
Sbjct: 59 PGPKGGYKPTSKAY-----EALSIQTLETEFVVPIY 89
Citing CD-Search:
Marchler-Bauer A, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR,
Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler GH, Mazumder R, Nikolskaya AN, Panchenko AR, Rao BS, Shoemaker BA,
Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, and Bryant SH (2003),
"CDD: a curated Entrez database of conserved domain alignments",
Nucleic Acids Res. 31:383-387.
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